BiosEXCHIM Life Science Technology and Chemicals, Ltd.

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crude GLYCERINE 70%min


crude GLYCERINE 70%min

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Isopropyl alcohol (also Isopropanol, propan-2-ol, 2-propanol or the abbreviation IPA)

Natural Flavour & Fragrances

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Product Description

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Food industry

In foods and beverages, glycerol serves as a humectant, solvent, and sweetener, and may help preserve foods. It is also used as filler in commercially prepared low-fat foods (e.g., cookies), and as a thickening agent in liqueurs. Glycerol and water are used to preserve certain types of leaves. As a sugar substitute, it has approximately 27 calories per teaspoon (sugar has 20) and is 60% as sweet as sucrose. Although it has about the same food energy as table sugar, it does not raise blood sugar levels, nor does it feed the bacteria that form plaques and cause dental cavities. As a food additive, glycerol is labeled as E number E422.

Glycerol is also used to manufacture mono- and di-glycerides for use as emulsifiers, as well as polyglycerol esters going into shortenings and margarine.

It is also used as a humectant (along with propylene glycol labelled as E1520 and/or E422) in the production of snus, a Swedish-style smokeless tobacco product.

As used in foods, glycerol is categorized by the American Dietetic Association as a carbohydrate. The U.S. Food and Drug Administration (FDA) carbohydrate designation includes all caloric macronutrients excluding protein and fat. Glycerol has a caloric density similar to table sugar, but a lower glycemic index and different metabolic pathway within the body, so some dietary advocates accept glycerol as a sweetener compatible with low carbohydrate diets.

[edit] Pharmaceutical and personal care applications

Glycerol is used in medical and pharmaceutical and personal care preparations, mainly as a means of improving smoothness, providing lubrication and as a humectant. It is found in allergen immunotherapies, cough syrups, elixirs and expectorants, toothpaste, mouthwashes, skin care products, shaving cream, hair care products, soaps and water-based personal lubricants. In solid dosage forms like tablets, glycerol is used as a tablet holding agent. For human consumption, glycerol is classified by the U.S. FDA among the sugar alcohols as a caloric macronutrient.

Glycerol is a component of glycerin soap, which is made from denatured alcohol, glycerol, sodium castorate (saponified Castor bean oil), saponified cocoa butter, saponified tallow, sucrose, water, and sometimes sodium laureth sulfate. Essential oils are added for fragrance. This kind of soap is used by people with sensitive, easily-irritated skin because it prevents skin dryness with its moisturizing properties. It draws moisture up through skin layers and slows or prevents excessive drying and evaporation. It is possible to make glycerol soap at home.

Used as a laxative when introduced into the rectum in suppository or small-volume (2–10 ml)(enema) form; irritates the anal mucosa and induces a hyperosmotic effect.

Topical pure or nearly pure glycerol is an effective treatment for psoriasis, burns, bites, cuts, rashes, bedsores, and calluses. It can be used orally to eliminate halitosis, as it is a contact bacterial desiccant. The same property makes it very helpful with periodontal disease; it penetrates biofilm quickly and eliminates bacterial colonies.

[edit] Surface science

Glycerol is shown to reduce the coefficient of friction of polymer coated surfaces by several orders of magnitude. This effect is attributed to the enhanced viscosity of glycerol-water solutions as compared to the pure water.[7]

[edit] Botanical extracts

When utilized in 'tincture' method extractions, specifically as a 10% solution, glycerol prevents tannins from precipitating in ethanol extracts of plants (tinctures). It is also used as a substitute for ethanol as a solvent in preparing herbal extractions. It is less extractive when utilized in tincture methodology and is approximately 30% more slowly absorbed by the body resulting in a much lower glycemic load. Fluid extract manufacturers often extract herbs in hot water before adding glycerin to make glycerites.[8][9]

When used as a primary true alcohol-free (e.g. no alcohol (i.e. ethanol) ever being used) botanical extraction solvent in innovative non-tincture based 'dynamic' methodologies, glycerol has been shown, both in literature and through extraction applications, to possess a high degree of extractive versatility for botanicals including removal of numerous constituents and complex compounds, with an extractive power that can rival that of alcohol or water/alcohol solutions. That Glycerol possess such high extractive power assumes that Glycerol, with its tri-atomic structure, is utilized with dynamic methodologies as opposed to standard passive 'tincturing' methodologies that are better suited to alcohol's di-atomic structure. Glycerol possesses the intrinsic property of not denaturing or rendering a botanical's constituents inert. Glycerol is a stable preserving agent for botanical extracts that, when utilized in proper concentrations in an extraction solvent base, does not allow inverting or REDOX of a finished extract's constituents over several years. Both Glycerol and ethanol are viable preserving agents. Glycerol is bacteriostatic in its action, and ethanol is bactericidal in its action.[10][11][12]

[edit] Antifreeze
Main article: antifreeze

Like ethylene glycol and propylene glycol, glycerol is a non-ionic kosmotrope that forms strong hydrogen bonds with water molecules, competing with water-water hydrogen bonds. This disrupts the crystal lattice formation of ice unless the temperature is significantly lowered. The minimum freezing point temperature is at about −36 °F / −37.8 °C corresponding to 60–70% glycerol in water.[13]

Glycerol was historically used as an anti-freeze for automotive applications before being replaced by ethylene glycol, which has a lower freezing point. While the minimum freezing point of a glycerol-water mixture is higher than an ethylene-glycol mixture, glycerol is not toxic and is being re-examined for use in automotive applications.[14][15]

In the laboratory, glycerol is a common component of solvents for enzymatic reagents stored at temperatures below 0 °C due to the depression of the freezing temperature of solutions with high concentrations of glycerol. It is also used as a cryoprotectant where the glycerol is dissolved in water to reduce damage by ice crystals to laboratory organisms that are stored in frozen solutions, such as bacteria, nematodes, and fruit flies.

[edit] Chemical intermediate

Glycerol is used to produce nitroglycerin, or glycerol trinitrate (GTN), which is an essential ingredient of smokeless gunpowder and various explosives such as dynamite, gelignite, and propellants like cordite. Reliance on soap-making to supply co-product glycerine made it difficult to increase production to meet wartime demand. Hence, synthetic glycerin processes were national defence priorities in the days leading up to World War II. GTN is commonly used to relieve angina pectoris, taken in the form of sub-lingual tablets, or as an aerosol spray.

A great deal of research is being conducted to try to make value-added products from crude glycerol (typically containing 20 % water and residual esterification catalyst) obtained from biodiesel production, as an alternative to disposal by incineration. The use of crude glycerin as an additive to biomass for a renewable energy source when combusted or gasified is also being explored.

  • Hydrogen gas production unit[16]
  • Glycerine acetate (as a potential fuel additive)[17]
  • Conversion to




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BiosEXCHIM Life Science Technology and Chemicals, Ltd.

Zabolotnogo 76 office 35, Kyiv, Kyiv, Ukraine




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