Product Description

D-calcium pantothenate is comform to USP*5/GB/T ********6 ,Pantothenic acid, also called vitamin B5 (a B vitamin), is a water-soluble vitamin. Pantothenic acid is an essential nutrient. Animals require pantothenic acid to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. The anion is called pantothenate.  Pantothenic acid is the amide between pantoic acid and β-alanine. Its name derives from the Greek pantothen, meaning "from everywhere", and small quantities of pantothenic acid are found in nearly every food, with high amounts in fortified whole-grain cereals, egg yolks, liver and dried mushrooms.[7][8] It is commonly found as its alcohol analog, the provitamin panthenol (pantothenol), and as calcium pantothenate.Pantothenic acid, also called vitamin B5 (a B vitamin), is a water-soluble vitamin. Pantothenic acid is an essential nutrient. Animals require pantothenic acid to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. The anion is called pantothenate.  Pantothenic acid is the amide between pantoic acid and β-alanine. Its name derives from the Greek pantothen, meaning "from everywhere", and small quantities of pantothenic acid are found in nearly every food, with high amounts in fortified whole-grain cereals, egg yolks, liver and dried mushrooms.[7][8] It is commonly found as its alcohol analog, the provitamin panthenol (pantothenol), and as calcium pantothenate.Content of pantothenic acid varies among manufactured and natural foods, especially fortified ready-to-eat cereals, infant formulas, energy bars and dried foods.[7] Major food sources of pantothenic acid are dried mushrooms, liver, dried egg yolks and sunflower seeds.[7] Whole grains are another good source of the vitamin, but milling removes much of the pantothenic acid, as it is found in the outer layers of whole grains.[*6] In animal feeds, the most important sources are alfalfa, cereal, fish meal, peanut meal, molasses, mushrooms, rice, wheat bran, and yeasts.[*7]



Supplementation[edit]

The derivative of pantothenic acid, pantothenol (panthenol), is a more stable form of the vitamin and is often used as a source of the vitamin in multivitamin supplements.[*7]:**7 Another common supplemental form of the vitamin is calcium pantothenate. Calcium pantothenate is often used in dietary supplements because, as a salt, it is more stable than pantothenic acid. Supplementation may improve oxygen utilization efficiency and reduce lactic acid accumulation in athletes.[*7]



Dietary reference intake[edit]

The Food and Nutrition Board of the U.S. Institute of Medicine updated Estimated Average Requirements (EARs) and Recommended Dietary Allowances (RDAs) for B vitamins in ***8. At that time there was not sufficient information to establish EARs and RDAs for pantothenic acid. In instances such as this, the Board sets Adequate Intakes (AIs), with the understanding that at some later date, AIs will be replaced by more exact information. As for safety, the FNB sets Tolerable Upper Intake Levels (known as ULs) for vitamins and minerals when evidence is sufficient. In the case of pantothenic acid there is no UL, as there is insufficient human data to identify adverse effects from high doses.[*8] The European Food Safety Authority reviewed the same safety question and also reached the conclusion that there was not sufficient evidence to set a UL for pantothenic acid.[*9] Collectively the EARs, RDAs and ULs are referred to as Dietary Reference Intakes.



For U.S. food and dietary supplement labeling purposes the amount in a serving is expressed as a percent of Daily Value (%DV). For pantothenic acid labeling purposes **0% of the Daily Value was *0 mg, but as of May ***6 it was revised to 5 mg. A table of the old and new adult Daily Values is provided at Reference Daily Intake. Food and supplement companies have until July *8, ***8 to comply with the change.



Pantothenic acid in the form of 4'phosphopantetheine is considered to be the more active form of the vitamin in the body; however, any derivative must be broken down to pantothenic acid before absorption.