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 Home > Sell Offers > Sell 6-Bromo-3,17-Dioxoetioallocholane
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WUHAN YUANCHENG TECHNOLOGY DEVELOPMENT Co., Ltd

    

Sell 6-Bromo-3,17-Dioxoetioallocholane


[China]
Posted Date: October 25, 2008    Expiry Date: December 10, 2009
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Description
We can supply 6-Bromo-3,17-Dioxoetioallocholane,which is a selective inhibitor of aromatase (estrogen synthetase) would be a useful pharmacological tool with potential therapeutic application. We have found that 6 alpha-bromoandrostenedione (6 alpha-BrA) is a competitive inhibitor of human placental aromatase with respect to androstenedione, with an apparent Ki of 3. 4 nM, while 6 beta-BrA is a mechanism-based irreversible inhibitor with an apparent Ki of 0.8 microM and a kinact of 0.025 min-1. Aromatase activity was measured by tritium release into water from the 1 beta position of [1(-3)H, 4(-14)C] androstenedione in reaction mixtures containing NADPH and the aromatase.
Other Information
Location:  China 
Minimum Order:   
Price for Minimum Order:   
  (This price is only for minimum order. for large quantities, please contact)
Sample Available:  No 
Related Categories: Organic Intermediate, Organic Salt, Pharmaceutical Chemicals
Related Keywords: 6-bromo-3, 17-dioxoetioallocholane, estrogen synthetase, 4(-14)c] androstenedione
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