Product Description

Papaya Extract Papain **0,****2,**0,**0 U/g

CAS#: ********4

Product name: Papaya Extract

Latin Name: Carica Papaya

Extract solvent: water / ethanol

Resolvable: dissolve water

Particle size: **0 mesh

Specification: Papain **0,****2,**0,**0 u/g

Apperance: Light yellow to white powder

What is Carica Papaya?

Carica papaya plants, and their fruits, are generally known as papayas. The papaya is also commonly called pawpaw orpapaw, although in North America the term pawpaw usually refers to plants in the unrelated North American genusAsimina, especially A. triloba, which produces large, edible fruits. The papaya is also sometimes called mugua, a name used in traditional Chinese medicine for Chaenomeles speciosa (flowering quince) or Pseudocydonia sinensis (Chinese quince).

Papaya fruit is a rich source of nutrients such as provitamin A carotenoids, vitamin C, B vitamins, dietary minerals and dietary fibre. Papaya skin, pulp and seeds also contain a variety of phytochemicals, including natural phenols. Danielone is a phytoalexin found in the papaya fruit. This compound showed high antifungal activity against Colletotrichum gloesporioides, a pathogenic fungus of papaya.

What is Papain?

Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.*2.2) enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis).

Papain belongs to a family of related proteins with a wide variety of activities, including endopeptidases, aminopeptidases, dipeptidyl peptidases and enzymes with both exo- and endo-peptidase activity. Members of the papain family are widespread, found in baculovirus, eubacteria, yeast, and practically all protozoa, plants and mammals. The proteins are typically lysosomal or secreted, and proteolytic cleavage of the propeptide is required for enzyme activation, although bleomycin hydrolase is cytosolic in fungi and mammals. Papain-like cysteine proteinases are essentially synthesised as inactive proenzymes (zymogens) with N-terminal propeptide regions. The activation process of these enzymes includes the removal of propeptide regions, which serve a variety of functions in vivo and in vitro. The pro-region is required for the proper folding of the newly synthesised enzyme, the inactivation of the peptidase domain and stabilisation of the enzyme against denaturing at neutral to alkaline pH conditions. Amino acid residues within the pro-region mediate their membrane association, and play a role in the transport of the proenzyme to lysosomes. Among the most notable features of propeptides is their ability to inhibit the activity of their cognate enzymes and that certain propeptides exhibit high selectivity for inhibition of the peptidases from which they originate.

What will Papain be used for?

1.It is a strong digestive enzyme and useful in serious digestive disorders such as bloating and chronic indigestion.
2.Unique ability of Papain is to break down protein and convert a portion of it into arginine because arginine influences the production of the human growth hormone.
3.It possesses potent spermicidal activity.

4.It is used in psoriasis, bleeding piles, jaundice, hepatosplenomegaly and counter irritant. 
5. An infusion of the leaves is used for various urinary

complaints.gonorrhea, colic, fever, beriberi, dressing for foul wounds etc.
6. It is used to remove skin lesions and improve damaged skin conditions.

Packing Detail: Packed in paper-drums and two plastic-bags inside. Barrels outside printed name, gross weight, batch number, production units, production time, effective time, storage and transportation methods.

Net Weight: *5kgs/drum.

Storage Situation: Stored in a well-closed container away from moisture and light.

Shelf Life:Two years under well Storage situation and stored away from direct sun light.