Product Description

Product name:Amentoflavone
CAS:********4
Purity:HPLC≥*8%
Specification:*0mg
Product Description:Amentoflavone is a constituent of a number of plants with medicinal properties, including Ginkgo biloba, Chamaecyparis obtusa (hinoki), Hypericum perforatum (St. John’s Wort) or Xerophyta plicata.
It is a biflavonoid (bis-apigenin coupled at 8 and 3' positions).
Amentoflavone can interact with many other medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are proteins used for drug metabolism in the body.It is also an inhibitor of human cathepsin B.
Amentoflavone has demonstrated some antimalarial activity in trials[4] significant affinities towards the delta*1, kappa opioid receptors (as an antagonist) and the allosteric (benzodiazepine) site on the GABAA receptors. (As a negative allosteric modulator)