Product Description

Coleus forskohlii is a botanical that has been used since ancient times in  Ayurvedic traditional medicine. The root portion of the plant has been traditionally used for medicinal purposes and contains the active constituent, forskolin. Coleus forskohlii is a perennial member of the mint (Lamiaceae) family and grows in the subtropical temperate climates of India, Nepal, Sri Lanka, and Thailand. Plant height is approximately **2 feet. The rootstock is typically golden brown, thick, fibrous, and radially spreading.   Roots are harvested in the fall, when forskolin is at its most concentrated and the color is the brightest.
Active Constituents
The diterpene forskolin, derived from the root of the plant, is the primary constituent of clinical interest in Coleus forskohlii.It was discovered by Western scientists in ***4 and was initially referred to as coleonol. Since that time, as other coleonols and diterpenoids have been identified, the name was changed to forskolin. Forskolin is responsible for virtually all pharmacological activities attributed to Coleus forskohlii which is present only in the root portion.
Mechanisms of Action
Forskolin’s primary mode of action is to increase cyclic adenosine monophosphate (cAMP) and cAMP mediated functions, via activation of the enzyme adenylate cyclase. Forskolin has been shown to increase cAMP formation in all eukaryotic cells except sperm, without hormonal activation of adenylate cyclase.
Nutraceutical applications
Coleus forskohlii is  considered to be a health powerhouse. Coleus is reported to have positive effect in -
§             Cardiovascular Health in conditions such as Hypertension, Angina and Congestive Heart Failure*
§             Skin Health in conditions such as eczema and allergic reactions *
§             Gastrointestinal health in conditions such as intestinal colic and mal absorption disorders or digestion*
§             Urogenital health in conditions such as uterine cramps and painful urination*
§             Respiratory system in conditions such as asthma*
§             Nervous system in conditions such as insomnia and convulsions*
§             Metabolic disorders  causing enhanced insulin secretion, increased thyroid hormone function and lipolysis(fat burning)
Coleus forskohlii is generally regarded safe and have little to no known adverse side effects. Although research indicates there is currently no daily recommended dose for Coleus forskohlii established by experts, people taking higher  doses usually take *0 mg, three times a day.
Savesta Product Specifications:
Coleus extract from Savesta is available as:
Coleus extract forskohlii- *0% Forskolin and Coleus forskohlii- *0% Forskolin
Packing: *5kg Double Polylined HPDE Drums.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.