Product Description

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST**7 and FST**4 containing **7 and **4 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which *7 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in **0 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh). Follistatin Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing **8 amino acids and having a total molecular mass of *1.5kDa. The FST is purified by proprietary chromatographic techniques.