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Contact Person Ms. Jonna Yuan
Wuxi, Jiangsu
Sip system , skid-mounted disc centrifuge separator for vaccine produce
Centrifugal separation technology for vaccine production
Disc separator with SIP&CIP is designed for aseptic processes, which is becoming increasingly important for handling sensitive products in the pharmaceutical, biotech and food industries. This is applicable for instance for the separation of proteins from fermentation solutions for pharmaceutical products, processing genetically modified micro-organisms or manufacturing starter cultures in the food and pharmaceutical industries, production of vaccines or the processing of genetically modified organisms. Phase separation by means of centrifugal force in a separator is a key aspect in the process involved. And this important step in the process must also take place under sterile conditions. This means that the entire separator system must be steam-sterilizable. All plant components such as fermenters and receiving tanks for the separated components are connected aseptically to the system.
Huading Separator has developed the clarifier BTSX-M series in steam-sterilizable design (SIP) specifically for these fields of application which has an hourly throughput capacity of 100 to 10,000 liters. The new disk type separator is suitable for the continuous clarification of suspensions, separating bacteria, mammalian cells, cell fragments and yeast under sterile conditions.
Product description
The complete disc separator with SIP&CIP is steam-sterilizable. The machine is sterilized at rotate using superheated steam at overpressure of 2.5 bar and a maximum possible temperature of 137 °C. After sterilization, the separator is blanketed with sterile air, which also cools down the machine, until the next product run. Sterilization avoids cross-contamination between different fermentation products which are treated in the same separator. Chemical cleaning in place (CIP) is carried out before the sterilization process (SIP). Cleaning liquid is circulated through the separator and the connected system.
A further aspect in the recovery of proteins in the separator is just as important as the prevention of product contamination: the guarantee of biocontainment. Therefore, Huading Separator offers the BTSX-M in steam-sterilizable design as an absolutely enclosed machine and plant concept which prevents toxic bacteria or living cell vaccines from escaping into the atmosphere.
Application:
insulin
monoclonal
antibodies
blood-derived
products
vaccine
sera
starter
cultures
pharmaceutical
proteins
animal cell
cultures
hormones
other applications, such
as E-Coli, inclusion bodies and mammalian cells starter cultures,
such as lactic acid bacteria, fermentation broth and enzymes
treatment of genetically engineered
microorganisms.
Main parameter
Voltage | 220-440V |
Power | 4-90KW |
HMI | SIEMENS |
PLC | SIEMENS |
Frequency converter | ABB or CUMARK |
Motor | ABB or WANNAN |
Machine installation
Country: | China |
Model No: | - |
FOB Price: | Get Latest Price |
Place of Origin: | - |
Price for Minimum Order: | - |
Minimum Order Quantity: | - |
Packaging Detail: | - |
Delivery Time: | - |
Supplying Ability: | - |
Payment Type: | - |
Product Group : | - |