Product Description

N-terminal pro-brain natriuretic peptide (NT-proBNP)
The form of brain natriuretic peptide in cardiomyocytes is brain natriuretic peptide precursor (also known as pro-brain natriuretic peptide, ProBNP), brain natriuretic peptide (BNP), N-terminal brain natriuretic peptide precursor (also known as amino terminal pro-brain natriuretic peptide, NT -ProBNP) Three types.
BNP is a polypeptide composed of *2 amino acids, containing a circular structure composed of *7 amino acids, and is a short peptide hormone secreted by the heart. The **4 amino acid Pre-pro-BNP synthesized in cardiomyocytes degrades into the BNP precursor (proBNP) containing **8 amino acids after entering the blood circulation, and proBNP forms a biologically active BNP and a Inactive *6 amino acid fragment NT-proBNP.
BNP is a biologically active protein with a half-life of *0 minutes, its in vitro stabilization time is only 1 hour, and its level is susceptible to the selected drugs, such as patients receiving recombinant human brain BNP (rh-BNP) for treatment Causes elevated levels of BNP in the blood. For the increase in BNP levels, it is difficult for clinicians to determine whether it is caused by drug therapy or cardiac dysfunction.
As an inactive NT-proBNP, the half-life is *****0 minutes, the in vitro stabilization time is up to *4 hours, it has higher sensitivity, and is not affected by rh-BNP, which is convenient for clinicians to accurately detect early and mild heart failure.
Human NT-proBNP                                Human NT-proBNP
Expression host: E.coli                           Expression host: HEK**3
Molecular weight: *3kD                          Molecular weight: ****7kD 
Concentration: **2mg/ml                         Concentration: **2mg/ml
Purity:> *0%                                   Purity:> *0% 
Storage environment: 1×PBS (pH7.4)               Storage environment: 1×PBS (pH7.4)
Storage conditions: short-term storage at 4℃, long-term storage at **0℃. Avoid repeated freezing and thawing.
Safety Tips: Not for human experiment
E. coli expresses NT-proBNP        mammalian cells **3 express NT-proBNP