Description

NO MORE LASER, PEELING, DERMOABRASION

SKINESSE

THE FIRST MESO-WHITENING EFFECT

Skinesse is the most effective and innovative sterile meso-cocktails for the hyperpigmentations, melasma, sun damage, age spots, discolorations, acne marks.

Skinesse contains a complete formula thanks its active ingredients that works in synergy.

The Skinesse’s action is fast and visible from the first session.

Composition

SKINESSE contains natural ingredients, based on Kudzu root nodules (symbiozomes).

In his natural enviroment, its main active compound: leghemoglobin is very important for the

Nitrogen species metabolism of the plant.

Similar structure to Hemoglobin in humans: acts as detoxyfier of free radicals skin lightener active

How it works?

–  Step 1: Controls the production of cGMP (involved in the mechanism of tyrosinase production)

and help to control melanogenesis through scavenging of nitrogen oxide (NO) radicals.

– Step 2: Accelerates the fading of UVB induced hyperpigmentation once it has devel

• Additional activities:

It also improves skin elasticity, stimulates production of collagen Curative action in

Hyperpigmentation and tanned skins (tests)

It also contains Isoflavones (Pueraria), antioxidant properties.

It is not cytotoxic and is very stable in water solutions

How it works?

– Step 1: Reduces NO· (melanogenic mediator) production

– Step 2: Inhibits Tyrosinase and other enzymes as TRP*1

– Step 3: Controls Melanosome transfer

• Additional activities:

– Antioxidant, protection against UVA/ UVB, inflammation inhibitor, improves cell metabolism,

protection of dermal matrix fibres

– Reduces the melanin quantity and also inhibits melanocytes dendricity, difficulting the

melanosome trasfer to keratinocytes, in just *0 days.

Albatin

It is a Phosphinic analogue of Alanine (Ala-P)

It is not cytotoxic and very stable in water solutions

How it works?

Albatin stabilizes DOPAchrome and inhibits the enzymatic activity of the

DOPAchrome tautomerase (TRP*2).

glutathione

Mechanism of action: it reduces the intermediates of the melanin.Glutation has a reducing group

SH which can form a complex with copper and also reduce dopaquinone to DOPA.