Description

A new indole alkaloid, picranitine, has been isolated from the seeds of Picralima nitida, along with five known indole alkaloids picratidine, akuammine, pseudoakuammine, akuammicine and akuammidine previously identified from the same source. Structures were elucidated through exhaustive spectral studies.
A method of preparing substantially purified alkaloids from seeds, stems, uit-rind and bark of a plant selected from Picralima nitida, for use in the treatment of protozoal diseases. .