PRODUCT DETAILS

 

 

DESCRIPTION

 

ONCASPAR (pegaspargase) is L-asparaginase (L-asparagine amidohydrolase) that is covalently conjugated to monomethoxypolyethylene glycol (mPEG). L-asparaginase is a tetrameric enzyme that is produced endogenously by E. coli and consists of identical *4.5 kDa subunits. Approximately *9 to *2 molecules of mPEG are linked to L-asparaginase; the molecular weight of each mPEG molecule is about 5 kDa. ONCASPAR activity is expressed in International Units. One International Unit of L-asparaginase is

 

defined as the amount of enzyme required to generate 1 micromole of ammonia per minute at pH 7.3 and *7C.

ONCASPAR is supplied as a clear, colorless, preservative-free, isotonic sterile solution in phosphate- buffered saline, pH 7.3. Each milliliter contains **0 , **0 International Units of pegaspargase, dibasic sodium phosphate, USP (5.*8 mg), monobasic sodium phosphate, USP, (1.*0 mg) and sodium chloride, USP (8.*0 mg) in water for injection, USP.

 

 

 

 

 

Therapeutic Indication:

Oncaspar is indicated as a component of antineoplastic combination therapy in Acute Lymphoblastic Leukaemia (ALL) in paediatric patients from birth to *8 years, and adult patients.

• Composition: Pegaspargase **0 Units/ ml.

• Pharmaceutical Form: Powder for Solution for Injection or Infusion.

• Method of Administration: Intravenous or intramuscular.

 

 

 

MORE DETAILS

 

 

• Drug TypeInjection

• Function: Anti-Cancer

• Suitable For: Suitable For All

• Physical Form: Liquid

• Recommended For: cancer treatment

• Ingredients: Oncaspar

• Brand: Oncaspar

 

 

 

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