Product Description
Description
Biologically active BMP*2 is a
homodimer, linked by a single disulfide bond. The monomers have
three intrachain disulfide bridges, forming a so-called cystine
knot. In vivo, the monomer is synthesized as a large precursor,
which after dimerization, is prote-olytically cleaved releasing the
smaller C-terminal fragment forming the mature dimer
.
Our product
produced in genetically engineered Eschericha coli is a non-active
aggregated form. After refolding and purification, the recombinant
human bone morphogenetic protein*2 is active and with high
homogeneity.
Source
:Escherichia
Coli.
Physical Appearance
:Sterile Filtered White lyophilized (freeze-dried)
powder.
Formulation
:Lyophilized from a concentrated (1mg/ml) solution
in water containing *0mM Sodium Acetic buffer,
pH4.0.
Solubility
:It is recommended to reconstitute the lyophilized
BMP*2 in distilled H2O not less than **0ug/ml, which can then be
further diluted to other aqueous
solutions.
Stability
:Lyophilized BMP*2 although stable at room
temperature for 3 weeks, should be stored desiccated below **8℃.
Upon reconstitution BMP*2 should be stored at 4℃ between **7 days
and for future use below **8℃ . For long term storage it is
recommended to add a carrier protein (0.1% HSA or
BSA).
Please
avoid freeze-thaw cycles.
Biological
Activity
Recombinant human
BMP*2 is fully biologically active when compared to standards. When
implanted in the mouse thighbone muscle and grow for *4 days,
Muscle tissue was harvested and examined biochemically for calcium
uptake. Our unit defined as 1 microgram calcium absorbed. The
specific activity is more than ***0
Units/mg
Country: |
China |
Model No: |
006
|
FOB Price: |
(Negotiable)
Get Latest Price
|
Place of Origin: |
- |
Price for Minimum Order: |
- |
Minimum Order Quantity: |
- |
Packaging Detail: |
- |
Delivery Time: |
- |
Supplying Ability: |
- |
Payment Type: |
- |
Product Group : |
- |