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It is used for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2 (ErbB2).[3]

It is also known as limonoate D-ring-lactone and limonoic acid di-delta-lactone. Chemically, it is a member of the class of compounds known as furanol

Limonoids are phytochemicals, abundant in citrus fruit and other plants of the families Rutaceae and Meliaceae. Currently limonoids are under investig

Methafurylene is an antihistamine and anticholinergic.

This colourless liquid is soluble in a wide range of solvents including lower alcohols. The molecule is a derivative of furan, containing both aldehyd

At high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opio

Nimbin is a chemical compound classified as a triterpenoid isolated from Azadirachta indica (neem tree). Nimbin is thought to be responsible for much

Niperotidine is a histamine antagonist selective for the H2 subtype. It was trialled as a treatment for excessive gastric acidity,[1] but withdrawn af

Pafuramidine also reached Phase III clinical trials for the treatment of first stage African sleeping sickness, but development was halted in 2008 ove

Perilla ketone is a natural terpenoid that consists of a furan ring with a six-carbon side chain containing a ketone functional group. It is a colorle

The antihypertensive characteristics of prazosin make it a second-line choice for the treatment of high blood pressure.

Positive results were reported in Phase II clinical trials in humans.[2]

It can be administered IV in intensive care units to critically ill patients (particularly geriatric ones) to reduce the risk of gastric bleeding.

Resmethrin is a pyrethroid insecticide with many uses, including control of the adult mosquito population.

Rosefuran has been established as a female sex pheromone of an acarid mite, Caloglyphus sp. Concentrations of less than 100 ng of synthetic rosefuran

Roseophilin is an antibiotic isolated from Streptomyces griscovirides shown to have antitumor activity.[1] The chemical structure can be considered in

It is structurally distinct from other naturally occurring hallucinogens (such as DMT, psilocybin, and mescaline) because it contains no nitrogen atom

Trimellitic anhydride chloride is a chemical compound used to produce polyamide-imide plastic.

In order to stabilize the Wortmannin molecule while not losing its therapeutic effect, numerous derivates were synthesized from Wortmannin[6]